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Figure S2: Ingenuity Path Designer representation of dendritic cell maturation with affected molecules in CpG_ODN treated blood samples for 4 h. Edges are displayed with various labels that describe the nature of the relationship between the nodes (e.g., P for phosphorylation, T for transcription). Nodes are displayed using various shapes that represent the functional class of the gene product. arrow head indicates gene A influences gene B). Line beginnings and endings illustrate the direction of the relationship (e.g. Direct relationships are indicated by solid lines. The intensity of the node color indicates the degree of up- (red) or down- (green) regulation. All edges are supported by at least one reference from the literature, from a textbook, or from canonical information stored in the Ingenuity Pathways Knowledge Base. Molecules are represented as nodes, and the biological relationship between two nodes is represented as an edge (line). Figure S1: Ingenuity Path Designer representation of Toll-like receptor signaling pathway with affected molecules in CpG_ODN treated blood samples for 4 h. A maximum of 5 terms are presented in the list. The terms are sorted from highest to lowest significance. Table S2: Over-represented Gene Ontology (GO) terms in the list of genes that were significantly regulated in blood samples treated with CpG_ODN or SB_ODN for 2 h compared to untreated samples at p≤0.01. Comparative list of determined expression changes of selected transcripts after 2 h of blood incubation with SB_ODN or CpG_ODN using RT 2 Profiler PCR Array and the microarray analysis. File S1: Table S1: Validation of microarray data using RT 2 Profiler PCR Array.